Table 3.
Blood biochemical parameters and cardiovascular risk factors according to genotype.
| Parameters | Carrier (−) n. 70 |
Carrier (+) n. 25 |
|---|---|---|
| Mean ± SD | Mean ± SD | |
| FG (mg/dL) | 91,33 ± 7,33 | 89,88 ± 7,15 |
| FI (μU/mL) | 7,98 ± 4,64 | 8,00 ± 4,35 |
| HOMA-IR | 3,35 ± 2,05 | 3,21 ± 1,70 |
| TC (mg/dL) | 203,44 ± 41,45 | 192,12 ± 31,96 |
| HDL-chol (mg/dL) | 65,16 ± 15,66 | 65,82 ± 14,38 |
| LDL-chol (mg/dL) | 116,18 ± 35,68 | 110,33 ± 32,53 |
| TG (mg/dL) | 96,12 ± 39,75 | 87,06 ± 33,79 |
| TC/HDL-chol ratio | 3,25 ± 0,85 | 3,03 ± 0,77 |
| LDL/HDL-chol ratio | 1,74 ± 0,79 | 1,71 ± 0,74 |
| Log TG/HDL-chol ratio | 1,58 ± 0,84 | 1,37 ± 0,58 |
| hs-CRP (μg/dL) | 0,73 ± 1,78 | 0,20 ± 0,50* |
| TNF-α (pg/mL) | 26,42 ± 15,33 | 20,62 ± 11,66 |
*P < 0.05.
Carrier (−): −308 TNF-α G/G genotype; carrier (+): −308 TNF-α A/G genotype; FG: fasting glucose; FI: fasting insulin; HOMA-IR: homeostasis model of assessment-insulin resistance; TC: total cholesterol; HDL-chol: HDL cholesterol; LDL-chol: LDL cholesterol; TG: triglycerides; hs-CRP: high-sensitivity C-reactive protein.