Table 1.
Criterion | Reason of inclusion | Reason of exclusion |
---|---|---|
Population | Qualifying disease: AD (diagnosed with established criteria, e.g., DSM-IV and NINCDS-ADRDA) Any severity of disease at baseline Community-/nursing-home-dwelling residents |
|
| ||
Perspective of the study | Prospective (concurrent) Comparative |
Retrospective (nonconcurrent, historical) |
| ||
Type of the study | RCT (open label or blinded) Crossover trials with a washout period between treatments |
Non-randomised CCT: cohort observational case control cross sectional noncomparative study |
| ||
Language | English | All others |
| ||
Study duration | Any | None |
| ||
Sample size | Any | None |
| ||
Intervention/treatments | Any dose of (i) donepezil (ii) memantine |
|
| ||
Control intervention/treatments | Placebo/usual care Any of the above interventions |
DSM-IV: Diagnostic and Statistical Manual of Mental Disorders; NINCDS-ADRDA: National Institute of Neurological and Communicative Disorders and Stroke and the AD and Related Disorders Association; CCT: controlled clinical trial.