Figure 3.
siRNA inhibition of CTGF mRNA expression. Serum starved HTFs were transfected with CTGF-siRNAs (siRNA1–siRNA5) or control siRNA, respectively, before being stimulated with TGF-β 2 for 24 h. (a) Comparison of relative expression of CTGF mRNA in cultured HTFs transfected with different siRNAs. Data were from three experiments. *P < 0.05, **P < 0.01 versus TGF-β 2(+). (b) Comparison of transcription levels of CTGF in HTFs under different conditions. Data were from three experiments. # P < 0.01 versus HTFs stimulated without TGF-β 2 in control group. *P < 0.01 versus HTFs treated with TGF-β 2 only.