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Blood urea nitrogen and serum creatinine.
| Group | Blood urea nitrogen (mg/dL) |
Serum creatinine (mg/dL) |
|---|---|---|
| Sham | 22.87 ± 0.59 | 0.49 ± 0.03 |
| UUO | 33.13 ± 0.51** | 0.98 ± 0.09** |
| UUO + ALA | 26.19 ± 0.51∗† | 0.62 ± 0.03† |
Values are mean ± SEM from 10 rats in each group. UUO: unilateral ureteral obstruction, UUO + ALA: unilateral ureteral obstruction plus alpha-lipoic acid, *P < 0.01, **P < 0.001 versus sham, † P < 0.001 versus UUO.
