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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Neurobiol Aging. 2013 Apr 9;34(8):10.1016/j.neurobiolaging.2013.02.016. doi: 10.1016/j.neurobiolaging.2013.02.016

Table 2.

Association of p.Arg47His in a cohort of clinically characterized and neuropathologically verified Alzheimer’s disease cases and controls (“TGenII”). AD Meta-Analysis: combination of TGenII Cohort results and Guerreiro et al., 2012.

Group MAF case MAF control Allele case Allele control Enrichment p-value
TGen II AD 0.0025 0.0009 5 | 1990 1 | 1158 2.8 0.4242
AD meta-analysis 0.0088 0.0027 27 | 3081 6 | 2263 3.3 0.0044