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a a E(NAD) represents the NAD+ form of SAHH; E-I(NAD) represents the complex of ribavirin bound to the NAD+ form of SAHH; E’I’(NADH) represents the complex of the oxidized ribavirin bound to the NADH form of SAHH; KI represents the equilibrium dissociation constant { KI = [E(NAD)][I]/[E-I(NAD)]}.
