Table 2. Family-based TDT analysis.

					Transmitted/	P-value
Gene	SNP	Reference SNP no.	n1	n2	Not-transmitted	Observed	Correcteda	OR	95% CI
ABCB1	e12/C1236T	rs1128503	150	108	T: 92/45 C: 45/92	5.1 × 10-5	4.6 × 10−4	2.04	1.45–2.99
	e21/G2677T e21/G2677A	rs2032582	150	111	G: 78/91 T: 96/64 A: 23/42	0.008	0.072	1.50b	1.08–2.09
	e26/C3435T	rs1045642	150	110	C: 56/87 T: 87/56	0.009	0.081	1.55	1.10–2.21
ABCC1	5'FR/G-260C	rs504348	150	7	G: 03/04 C: 04/03	0.705	−	1.33	0.23–9.10
ABCC2	e1/C-24T	rs717620	150	76	C: 41/50 T: 50/41	0.345	−	1.24	0.811.93
	e10/G1249A	rs2273697	150	53	G: 34/22 A: 22/34	0.107	−	1.55	0.88–2.77
	e5/C421A	rs2231142	150	110	C: 70/62 A: 62/70	0.486	−	1.13	0.79–1.62
ABCG2	e2/G34A	rs2231137	150	105	G: 54/71 A: 71/54	0.127	−	1.32	0.91–1.91
	I9/T-357C	rs2054576	150	91	T: 59/51 C: 51/59	0.445	−	1.16	0.78–1.72

Abbreviations: CI, confidence Interval; OR, odds ratio; n1, number of family samples which were successfully genotyped; n2, number families with at least one heterozygote parent.

P-value of <0.01 are highlighted in bold.

^aAfter adjustment for multiple comparisons (N=9).

^bOR for T-allele.