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. 2013 Oct 18;191(11):5669–5676. doi: 10.4049/jimmunol.1301343

FIGURE 3.

FIGURE 3.

IFN levels following in vitro EBV infection vary with age and serostatus to CMV. CBMC or PBMC derived from 2- or 5-y-old children were subjected to in vitro EBV infection, and cell culture supernatants were collected and examined for cytokines. Secreted levels of (A) IL-10, (B) IFN-α and (C, D) IFN-γ. Shaded histograms represent control cultures and unfilled EBV-infected cultures. In (D), data from the 2-y-old children are divided into CMV-seronegative (CMV−) or -seropositive (CMV+). CB (day 7, n = 3; day 14, n = 6–7), 2-y-olds (day 7, n = 6; day 14, n = 12–16; CMV− day 7, n = 3, day 14, n = 7–9; CMV+ day 7, n = 3, day 14, n = 5–6) and 5-y-olds (day 7, n = 3; day 14, n = 7–8). *p < 0.05, **p < 0.01.