. 2013 Oct 18;191(11):5669–5676. doi: 10.4049/jimmunol.1301343

Table I. B cell subset proportions ex vivo in children of different ages.

Frequency of Cells (%)	Cord Blood (n = 7)	2-y-Olds (n = 19)	5-y-Olds (n = 7)	p Value
CD19⁺	8.5 (4.6–13.4)	16.2 (8.5–28)	14.6 (9.7–19.5)	^°<0.001, ^§<0.05, ^¶n.s.
CD19⁺IgD⁺CD27⁻	90.7 (85.8–95.9)	82.7 (72.2–89.8)	73.5 (63.3–79.4)	^°<0.001, ^§<0.001, ^¶<0.01
CD19⁺IgD⁺CD27⁺	1.9 (1.1–2.3)	5.4 (2.7–13.6)	7.8 (4.7–10.5)	^°<0.001, ^§<0.001, ^¶n.s.
CD19⁺IgD⁻CD27⁺	0.4 (0.1–0.5)	5.7 (2.3–10.2)	9.7 (7.2–19.8)	^°<0.001, ^§<0.001, ^¶<0.001
CD19⁺IgD⁻CD27⁻	6.8 (2.8–12)	4.9 (2.1–13.5)	8.2 (6.6–11.6)	^°n.s., ^§n.s., ^¶<0.01

Numbers indicate median (range).

°Comparison CB and 2-y-old children.

^§Comparison CB and 5-y-old children.

^¶Comparison 2- and 5-y-old children.