Table 1.
Demographic and laboratory features of non-alcoholic steatohepatitis, simple steatosis and healthy control groups
| Factor | NASH group (n = 62) | Steatosis group (n = 32) | Healthy control group (n = 30) | P-value |
| Age mean ± SD | 48.81 ± 12.21 | 47.25 ± 12.58 | 48.03 ± 9.54 | NS |
| Gender (male) | 30 (48.3) | 18 (56.2) | 18 (60) | NS |
| BMI (kg/m2) | 27.13 ± 0.37 | 25.97 ± 0.67 | 24.22 ± 0.45 | < 0.01 |
| Hemoglobin (g/dL) | 14.10 ± 0.16 | 14.51 ± 0.28 | 13.91 ± 0.11 | NS |
| Platelet (× 103/mL) | 245.5 ± 34.73 | 244.5 ± 13.8 | 260 ± 4.47 | NS |
| WBC (k/UL) | 6950 ± 319 | 7250 ± 330 | 7350 ± 146 | NS |
| Neutrophil ratio | 59.39% ± 1.20% | 59.87% ± 1.20% | 59% ± 1.1% | NS |
| Lymphocyte ratio | 31.29% ± 1.09% | 29.88% ± 1.10% | 32% ± 0.78% | NS |
| RDW | 14.28% ± 0.25% | 13.37% ± 0.12% | 12.96% ± 0.14% | < 0.01 |
| MPV (fL) | 8.63 ± 1.30 | 8.49 ± 1.06 | 8.20 ± 0.59 | NS |
| MCV (fL) | 86.34 ± 0.88 | 87.98 ± 1.37 | 85.5 ± 0.82 | NS |
| ALT (IU/L) | 54 ± 8.1 | 45 ± 3.97 | 32.5 ± 1.49 | < 0.01 |
| AST (IU/L) | 40.05 ± 6.04 | 40.05 ± 3.01 | 24 ± 1.39 | < 0.01 |
| ALP (IU/L) | 87.5 ± 9.09 | 81.5 ± 3.91 | 61 ± 1.87 | < 0.01 |
| GGT (IU/L) | 61 ± 13.4 | 32 ± 3.4 | 27 ± 2.5 | < 0.01 |
| Albumin (g/dL) | 4.36 ± 0.73 | 4.5 ± 0.42 | 4.9 ± 0.75 | < 0.01 |
| Creatinine | 0.78 ± 0.033 | 0.79 ± 0.023 | 0.72 ± 0.014 | NS |
| BUN (mg /dL) | 12.25 ± 0.85 | 14.2 ± 0.67 | 13.46 ± 0.71 | NS |
| Diabetes mellitus | 19 (30.6) | 9 (28.1) | 0 (0) | NS |
| Hypertension | 22 (35.4) | 7 (21.8) | 0 (0) | NS |
Values are presented as n (%) frequencies, median ± SE for skewed distributed variables. BMI: Body-mass index; RDW: Red cell distribution width; MPV: Mean platelet volume; NS: Not significant; ALT: Alanine aminotransaminase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; GGT: γ glutamyl transferase; WBC: White blood cell; MCV: Mean corpuscle volume; BUN: Blood urine nitrogen.