Figure 3. The water pool around homocitrate in the MoFe protein (Av, PDB 3U7Q).

The hydrogen bonded water molecules of the proton wire are coloured orange. The water molecules extending from homocitrate towards the cyan pocket are coloured brown. Between these two sets of water molecules is a compact cluster of water molecules coloured magenta. Connecting lines from the water molecules signify contacts at hydrogen bond distances. Two significant amino acids, Arg^105B and Arg^96A, are drawn with atom spheres. Cartoon representations of significant parts of chain A (green) and B (red) are included.