Table 2.
Reference | Adequate sequence generation? | Allocation concealment? | Blinding? | Incomplete outcome data addressed? |
---|---|---|---|---|
B LACTIS
|
|
|
|
|
Barclay 2003 [4] plus unpublished data |
Unclear* |
Yes |
Yes |
No** |
Gibson 2009 [7] |
Yes |
Yes |
Yes |
Yes |
Holscher 2012 [8] |
Unclear |
Unclear |
Yes |
Yes |
Urban 2008 [5] plus unpublished data |
Yes |
Yes |
Yes |
No** |
Velaphi 2008 [9] |
Unclear |
Unclear |
Yes |
No** |
Weizman 2006 [3] |
Yes |
Unclear |
Yes |
Yes |
Ziegler 2003 [10] |
Unclear |
Unclear |
Unclear |
No** |
LACTOBACILLUS GG
|
|
|
|
|
Scalabrin 2009 [12] |
Yes |
Yes |
Yes |
No |
Vendt 2006 [11] | Yes | Unclear | Yes | Yes |
In all cases, an answer of ‘yes’ indicates a low risk of bias, and an answer of ‘no’ indicates a high risk of bias.
* The randomization procedure was changed during the study because of a problem with formula supply.
** A drop-out rate >20%.