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. Author manuscript; available in PMC: 2013 Nov 18.
Published in final edited form as: Compr Physiol. 2013 Jan;3(1):10.1002/cphy.c120019. doi: 10.1002/cphy.c120019

Figure 10.

Figure 10

Cholangiocyte transport of organic anions and cations. Located at the cholangiocyte apical plasma membrane is (1) multidrug resistance 1 protein that excretes organic cations into bile. Located at the basolateral plasma membrane are transporters effectuating efflux of organic anions from cholangiocytes into the peribiliary vascular plexus: multidrug-associated proteins (2) MPR3/Mpr3 and (3) MPR4, (4) organic anion transporting polypeptide 3, and (5) organic solute transporter Ostα-Ostβ. TJ, tight junction. [Adapted from Masyuk et al. (183), with permission].