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. 2013 Oct 21;110(45):18274–18278. doi: 10.1073/pnas.1310163110

Fig. 2.

Fig. 2.

c-Fos activity by group and age. (A) The density of c-Fos protein in the amygdala following exposure to the threatening context (i.e., novel cage) was elevated in ELS mice across development, similar to adolescent controls. The age by experimental group interaction [F = 2.132; P < 0.05; n = 5–8 mice per experimental group (10–15 slices per animal)] shows the most robust differences were between the preadolescent ELS and control groups (t = 4.71; P < 0.001). Data are expressed as means ± SEM. (B) The density of c-Fos protein in the IL increases with age [F = 2.466; P < 0.05; n = 3–8 mice per experimental group (10–15 slices per animal)]. All data expressed as means ± SEM.