TABLE 3.

Direct comparison of equicaloric high-fat compared with high-sugar milkshakes on BOLD response

	Hemisphere of the brain	MNI1 coordinates x, y, z	k2	Peak Z	r3	Peak P
High-fat compared with high-sugar milkshakes (high-fat/low-sugar compared with low-fat/high-sugar milkshakes)
Hippocampus	Left	−21, −37, 10	42	5.15	0.50	1.3 × 10−7
Caudate	Left	−15, −23, 1	43	4.97	0.48	3.4 × 10−7
Postcentral gyrus	Left	−21, −37, 70	34	4.46	0.43	4.2 × 10−6
		−15, −31, 73		3.86	0.37	—
Inferior frontal gyrus	Left	−45, 23, 25	61	4.43	0.43	4.7 × 10−6
Hippocampus	Right	15, −34, 10	39	4.88	0.47	5.3 × 10−7
		18, −25, 19		4.47	0.43	—
Hippocampus	Right	24,−37, 7		3.95	0.38	3.9 × 10−5
Cerebellum	Right	15, −76, −32	37	4.19	0.41	1.4 × 10−5
		9, −79, −41		3.77	0.36	—
		27, −79, −41		3.76	0.36	—
Caudate	Right	18, 23, 1	27	4.06	0.39	2.4 × 10−5
Postcentral gyrus	Right	21, −37, 70	15	3.97	0.38	3.6 × 10−5
Frontal pole	Left	−24, 59, 7	15	3.61	0.35	1.5 × 10−4
		−12, 62, 4		3.42	0.33	—
High-sugar compared with high-fat milkshakes (low-fat/high-sugar compared with high-fat/low-sugar milkshakes)
Insula	Right	36, −7, 7	78	5.32	0.52	5.1 × 10−8
Putamen	Right	30, −13, −5		3.70	0.36	1.8 × 10−4
Insula	Right	42, 5, −5		3.51	0.34	2.2 × 10−4
Insula/putamen	Left	−36, −7, 7	154	4.59	0.45	2.2 × 10−7
Rolandic operculum	Left	−51, 5, −2		4.41	0.42	5.2 × 10−6
Insula	Left	−36, −4, −2		4.22	0.41	1.2 × 10−5
Rolandic operculum	Right	63, −13, 19	70	4.18	0.40	1.4 × 10−5
Thalamus	Left	−15, −25, 7	15	3.68	0.36	1.2 × 10−4
		−9, −16, 7		3.34	0.32	4.2 × 10−4

¹MNI, Montreal Neurological Institute.

²Cluster size. Clusters may contain more than one brain region as indicated by multiple names or P values under one cluster size.

³Pearson's product-moment correlation (calculated as Z ).