Table 2.
Pulmonary function test results in healthy volunteers and acromegalic patients (absolute values)
| Control group (n = 20) | Acromegaly group (n = 20) | p | |
|---|---|---|---|
| FVC (L) |
3.27 ± 0.85 |
3.67 ± 1.03 |
0.186 |
| FEV1 (L) |
2.60 ± 0.65 |
2.92 ± 0.79 |
0.168 |
| FEV1/FVC (%) |
84.7 ± 3.25 |
79.8 ± 4.11 |
0.598 |
| FEF25-75% (L/s) |
2.61 ± 0.71 |
3.08 ± 1.16 |
0.130 |
| FEF25-75%/FVC (%) |
79.4 ± 6.06 |
83.6 ± 7.93 |
0.605 |
| MIP (cm H2O) |
-81.3 ± 29.4 |
-63.6 ± 28.9 |
0.063 |
| MEP (cm H2O) |
121 ± 32.9 |
92.3 ± 30.79 |
0.001 |
| TLC (L) |
4.83 ± 0.98 |
5.61 ± 1.09 |
0.023 |
| RV (L) |
1.55 ± 0.32 |
2.04 ± 0.38 |
<0.001 |
| RV/TLC (%) |
32.6 ± 6.89 |
37.5 ± 8.94 |
0.063 |
| Raw (cm H2O/L/s) |
2.31 ± 0.58 |
3.82 ± 0.49 |
0.039 |
| DLCO (ml/min/mm Hg) |
22.6 ± 5.66 |
23.3 ± 6.46 |
0.713 |
| VA (L) |
4.61 ± 1.33 |
4.92 ± 1.19 |
0.443 |
| DLCO/VA (ml/min/mm Hg/L) |
5.08 ± 1.06 |
4.72 ± 0.64 |
0.205 |
| TLC-VA difference (L) | 0.19 ± 0.61 | 0.69 ± 0.46 | 0.021 |
Values are means ± SD or numbers (%). DLCO, diffusing capacity for carbon monoxide, FEF25-75%, forced expiratory flow during the middle half of the FVC; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; MEP, maximal expiratory pressure; MIP, maximal inspiratory pressure; Raw, airway resistance; RV, residual volume; TLC, total lung capacity; VA, alveolar volume.