Table 3.
Pulmonary function test results in healthy volunteers and acromegalic patients (% predicted values)
| Control group (n = 20) | Acromegaly group (n = 20) | p | |
|---|---|---|---|
| FVC (% predicted) |
98.9 ± 21.4 |
107.1 ± 15.9 |
0.028 |
| FEV1 (% predicted) |
96.2 ± 11.9 |
104.8 ± 15.5 |
0.057 |
| FEV1/FVC (% predicted) |
97.2 ± 3.30 |
94.0 ± 4.86 |
0.572 |
| FEF25-75% (% predicted) |
91.5 ± 18.9 |
105.9 ± 20.1 |
0.261 |
| FEF25-75%/FVC (% predicted) |
95.2 ± 6.77 |
99.4 ± 7.05 |
0.630 |
| MIP (% predicted) |
85.3 ± 24.1 |
71.4 ± 27.8 |
0.005 |
| MEP (% predicted) |
103.7 ± 19.2 |
55.9 ± 17.1 |
<0.001 |
| TLC (% predicted) |
93.7 ± 7.60 |
107.3 ± 12.9 |
0.002 |
| RV (% predicted) |
90.0 ± 14.6 |
114.1 ± 22.7 |
<0.001 |
| RV/TLC (% predicted) |
94.9 ± 13.4 |
107.1 ± 27.2 |
0.068 |
| DLCO (% predicted) |
103.1 ± 13.9 |
103.7 ± 24.4 |
0.968 |
| VA (% predicted) |
90.5 ± 15.5 |
93.6 ± 12.2 |
0.147 |
| DLCO/VA (% predicted) | 116.4 ± 22.3 | 110.2 ± 18.5 | 0.346 |
Values are means ± SD or numbers (%). DLCO, diffusing capacity for carbon monoxide, FEF25-75%, forced expiratory flow during the middle half of the FVC; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; MEP, maximal expiratory pressure; MIP, maximal inspiratory pressure; Raw, airway resistance; RV, residual volume; TLC, total lung capacity; VA, alveolar volume.