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. Author manuscript; available in PMC: 2013 Nov 18.
Published in final edited form as: JAMA. 2011 Sep 21;306(11):10.1001/jama.2011.1333. doi: 10.1001/jama.2011.1333

Table 2.

PROSTQA Model–Predicted Probabilities of Men Having Functional Erections Suitable for Intercourse 2 Years After Radical Prostatectomy

Planned
Surgical Technique
Patient
Age, y
Pretreatment
PSA Level,
ng/mL
Predicted Functional Erections
After Treatment, % (95% CI)
(by Pretreatment
Sexual HRQOL Score)a,b
67 83 100
Nerve-sparing 50 ≤10 35 (25–45) 52 (43–61) 70 (61–77)
>10 18 (9–34) 32 (18–49) 50 (32–68)
60 ≤10 23 (18–30) 38 (33–44) 57 (49–64)
>10 11 (0–21) 21 (12–34) 36 (22–53)
70 ≤10 15 (10–22) 26 (19–35) 43 (32–55)
>10 7 (3–14) 13 (7–24) 24 (13–41)
Non–nerve-sparing 50 ≤10 13 (5–30) 23 (9–46) 39 (18–64)
>10 6 (2–18) 11 (4–31) 21 (7–48)
60 ≤10 8 (3–19) 14 (6–32) 27 (12–50)
>10 3 (1–11) 7 (2–19) 13 (4–34)
70 ≤10 5 (2–12) 9 (3–22) 17 (7–37)
>10 2 (1–7) 4 (1–12) 8 (3–23)

Abbreviations: HRQOL, health-related quality of life; PROSTQA, Prostate Cancer Outcomes and Satisfaction With Treatment Quality Assessment; PSA, prostate-specific antigen.

a

Specific values of pretreatment sexual functioning (Expanded Prostate Cancer Index Composite scores of 67, 83, and 100; range of 0–100, with a higher score representing better function) are tabulated to represent cohort distribution (25th, 50th, and 75th percentiles of scores among prostatectomy-treated patients) as well as to reflect a clinically relevant set of possible pretreatment sexual functioning. Across all treatment groups, these percentiles correspond to 358 patients (36%) with pretreatment sexual HRQOL scores of 67 or less, 441 (45%) with scores of 68–99, and 186 (19%) with scores of 100.

b

Individual model-predicted probabilities were calculated using the inverse logistic function {exp[X′ β]/[1 + exp(X′ β)]}, where X′ β is the sum with X representing individual characteristics observed and β representing the associated model parameter estimates for the individual characteristics in Table 1.