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Ki values for clofarabine, cladribine and fludarabine at A1, A2A, and A3 receptor subtypes. Values are Ki from radioligand binding studies given in nM with 95% confidence intervals in parentheses (n=3).
| A1 | A2A | A3 | |
|---|---|---|---|
| clofarabine | 274 (224-335) | 17,100 (10,900-26,900) | 10,600 (7,190-15,800) |
| cladribine | 1,570 (1,450-1,710) | 15,100 (11,300-20,200) | > 100,000 |
| fludarabine | 3,000 (2,330-3,870) | > 100,000 | > 100,000 |
