Figure 6.

An overlap of the Adeh_3718 sensor domain with bound acetate and the sensor domain of TlpB complexed with acetamide (PDB code, 3ub7) is shown. The two structures were overlapped with SSM routine in Coot. Adeh_3718 sensor is shown in cyan and TlpB sensor in pink. The bound small molecules acetate and acetamide are shown in ball-stick representation with atom type colors (carbon: green, oxygen: red, nitrogen: blue). Note the similarity of the two structures and the binding sites. The TlpB sensor has an additional helix at the C-terminus (residues 188–201) that is not present in Adeh_3718 sensor; this helix is not shown in the figure for clarity purposes.