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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: FEBS J. 2013 Jun 7;280(14):10.1111/febs.12328. doi: 10.1111/febs.12328

Figure 7. Effect of the N-terminal mutations on activity of hBD3.

Figure 7

Panels A through D describe inhibition of the SDF-1α-dependent Ca2+-mobilization by several N-terminal hBD-3 mutants. A: mutant H2N (replace G1 through Y10 of hBD3 with GIGDPVT)); B: mutant NA2 (N4E/T5E/K8A-hBD3); C: mutant NC (N4R/T5R-hBD3); D: mutant K8A; E: inhibition of high-affinity SDF-1α binding by mutants H2N and NA2.