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PDS facilitates the adsorption of intact amyloid fibrils to plate well walls. Aβ1–40 fibrils were incubated in the absence (green) or in the presence of 25 or 50 µg/mL PDS (red and blue, respectively), as described in Figure 1(C). After 35 h of incubation, the plate was sonicated for 1 h, and the ThT fluorescence measured again. Most of the ThT fluorescence of PDS samples is recovered, indicating that Aβ fibrils are adsorbed to the well walls.
