Table II.
Proteins (n = 15) with a Fold Change in A. fumigatus ΔelfA Compared with A. fumigatus After Exposure to 2 mM H2O2 Following Identification by 2DE and LC-MS/MS
Spot no. | Annotation name | CADRE IDa | Fold change | tpI | tMW | % Sequence coverage |
---|---|---|---|---|---|---|
644 | Vacuolar dynamin-like GTPase VpsA | AFUA_5G02360 | +7.8 | 8.30 | 78,425 | 18 |
635 | Vacuolar dynamin-like GTPase VpsA | AFUA_5G02360 | +4.3 | 8.30 | 78,425 | 3 |
652 | Vacuolar dynamin-like GTPase VpsA | AFUA_5G02360 | + 3.0 | 8.30 | 78,425 | 19 |
592 | Mitochondrial outer membrane translocase receptor (TOM70) putative | AFUA_2G01660 | +1.9 | 5.40 | 70,009 | 10 |
767 | ATP citrate lyase, subunit 1, putative | AFUA_6G10650 | +1.9 | 8.60 | 78,828 | 33 |
368 | Carbamoyl-phosphate synthase, large subunit | AFUA_2G10070 | +1.7 | 6.10 | 129,214 | 25 |
567 | Cobalamin-independent methionine synthase Met H/D | AFUA_4G07360 | +1.7 | 6.33 | 87,072 | 31 |
1377 | Metallo-β-lactamase family protein | AFUA_5G12770 | +1.6 | 5.60 | 34,197 | 30 |
526 | Cysteinyl-tRNA synthetase | AFUA_5G09610 | +1.5 | 5.95 | 91,041 | 25 |
630 | Glycerol-3-phosphate dehydrogenase, mitochondrial | AFUA_1G08810 | +1.5 | 6.71 | 76,899 | 31 |
694 | Vacuolar ATP synthase catalytic subunit A | AFUA_5G02370 | +1.5 | 5.83 | 75,329 | 43 |
787 | Pyruvate decarboxylase PdcA | AFUA_3G11070 | +1.5 | 6.08 | 63,307 | 33 |
2078 | ATP citrate lyase, subunit 1 | AFUA_6G10650 | +1.5 | 8.66 | 79,359 | 42 |
1494 | RAS small monomeric GTPase RasA | AFUA_5G11230 | −2.2 | 4.97 | 24,292 | 61 |
1167 | Nuclear pore complex protein (SonA) | AFUA_1G09020 | −2.1 | 7.61 | 40,220 | 32 |
2066 | Proteasome regulatory Particle Subunit (RpnL) | AFUA_3G08940 | −1.8 | 4.9 | 31,201 | 55 |
358 | Pyruvate carboxylase | AFUA_4G07710 | −1.6 | 6.23 | 132,003 | 27 |
1616 | Haloalkanoic acid dehalogenase | AFUA_6G14460 | −1.6 | 6.19 | 26,716 | 39 |