Table 3.
Resting cardiovascular variables obtained before the administration of retigabine (3 mg·kg−1) or vehicle
| Pretreatment | Saline (n = 5) | Propranolol (n = 6) | CGP 20712A (n = 6) | ICI 118551 (n = 6) |
|---|---|---|---|---|
| HR (beats·min−1) | 340 ± 9 | 322 ± 6 | 326 ± 8 | 353 ± 15 |
| MAP (mmHg) | 100 ± 2 | 107 ± 2 | 100 ± 2 | 110 ± 3 |
| RVC (U) | 84 ± 4 | 82 ± 7 | 83 ± 5 | 84 ± 10 |
| MVC (U) | 68 ± 6 | 66 ± 5 | 95 ± 13 | 86 ± 10 |
| HVC (U) | 50 ± 8 | 45 ± 3 | 44 ± 6 | 40 ± 6 |
Units (U) for VC are (kHz·mmHg−1)103. Values are mean ± SEM. For abbreviations see Table 1 (Experiment 2).