Table 1.
Effects of quercetin and allopurinol on body weight, relative weight percentage of liver and blood glucose levels in STZ-induced diabetic rats
| Group | Dose (mg·kg−1) | Body weight (g) | Relative weight percentage of liver (%) | Blood glucose (mmol L−1) |
|---|---|---|---|---|
| Normal control | – | 442.2 ± 6.2 | 2.57 ± 0.09 | 4.90 ± 0.12 |
| STZ control | – | 212.2 ± 16.2+++ | 5.26 ± 0.18+++ | 15.48 ± 1.08+++ |
| STZ + quercetin | 25 | 281.3 ± 10.7* | 5.05 ± 0.11 | 9.53 ± 0.79*** |
| STZ + quercetin | 50 | 368.5 ± 28.1*** | 4.61 ± 0.20* | 9.01 ± 1.26*** |
| STZ + quercetin | 100 | 368.4 ± 31.8*** | 4.01 ± 0.21*** | 7.88 ± 1.25*** |
| STZ + allopurinol | 10 | 362.2 ± 24.6*** | 3.82 ± 0.08*** | 7.55 ± 0.92*** |
These results are expressed as mean ± SEM, n = 8. Normal control, control rats; STZ control, STZ-treated rats; STZ + quercetin, STZ-treated rats fed with quercetin; STZ + allopurinol, STZ-treated rats fed with allopurinol.
+++
P < 0.001 compared to normal control group,
*
P < 0.05, **P < 0.01,
***
P < 0.001 compared to STZ control group.