Table 2.
Multiple logistic regression regarding different psychotropic drug use
| Odds ratio | 95% confidence interval | p-value | |
|---|---|---|---|
|
Antidepressants (N06A) |
|
|
|
| Male sex |
0.727 |
0.381-1.385 |
0.332 |
| Higher age |
0.932 |
0.897-0.969 |
0.000 |
| Moderate cognitive impairmenta |
1.971 |
1.072-3.622 |
0.029 |
| Mild cognitive impairmenta |
0.933 |
0.460-1.894 |
0.848 |
|
Anxiolytics (N05B) |
|
|
|
| Male sex |
0.522 |
0.181-1.505 |
0.229 |
| Higher age |
0.985 |
0.939-1.032 |
0.521 |
| Moderate cognitive impairmenta |
0.606 |
0.242-1.514 |
0.283 |
| Mild cognitive impairmenta |
1.331 |
0.509-3.481 |
0.560 |
| Verbally disruptive/attention- |
2.193 |
1.389-3.462 |
0.001 |
| seeking behavior |
|
|
|
|
Hypnotics and sedatives (N05C) |
|
|
|
| Male sex |
1.769 |
0.917-3.413 |
0.089 |
| Higher age |
0.932 |
0.896-0.971 |
0.001 |
| Moderate cognitive impairmenta |
1.401 |
0.725-2.705 |
0.316 |
| Mild cognitive impairmenta |
3.627 |
1.685-7.810 |
0.001 |
| Disoriented symptoms | 1.545 | 1.169-2.041 | 0.002 |
Model Cox and Snell R2: 0.078, concordance between observed and predicted value: 65.4% (antidepressants): 0.070/85.5% (anxiolytics): 0.138/69.9% (hypnotics and sedatives). aCognitive score ranges from 0–27 points and a score of less than 24 is considered to indicate cognitive impairment. The scale is subdivided into three groups, 0–7 (severe cognitive impairment), 8–15 (moderate cognitive impairment) and 16–23 (mild cognitive impairment). Severe cognitive impairment is reference category.