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. 2013 Jul 4;5(2):70–75. doi: 10.1556/IMAS.5.2013.2.3

Table III.

Serum parameters in effect of MARS treatments. Albumin and INR results are also influenced by exogenous supplement. Decrease in the level of cholinesterase, and the slight increase of ammonia level shows that MARS therapy could not entirely keep up with the progression of liver failure

Parameter Unit Before MARS After MARS Percent change p Value

Carbamide mmol/L 20.5 ± 12.0 13.7 ± 6.7 −0.3318 0.0488
Creatinine μmol/L 213.6 ± 85.7 151.8 ± 51.7 −0.2891 0.0155
Bilirubin, total μmol/L 411.4 ± 250.0 325.6 ± 156.0 −0.2085 0.0126
Bilirubin, conj. mmol/L 318.8 ± 237.0 224.0 ± 147.5 −0.2972 0.0077
ALP U/L 272.7 ± 115.8 234.6 ± 89.5 −0.1397 0.0607
SGOT U/L 535.5 ± 746.7 375.9 ± 379.7 −0.2981 0.0856
SGPT U/L 420.2 ± 450.9 368.4 ± 353.7 −0.1232 0.0152
GGT U/L 108.9 ± 65.0 92.9 ± 54.5 −0.147 0.0210
LDH U/L 702.0 ± 382.3 462.9 ± 272.4 −0.3406 0.1122
Lactate mmol/L 7.2 ± 1.5 4.7 ± 1.8 −0.3431 N/A

Cholinesterase U/L 5897.9 ± 1514.2 5198.5 ± 1348.2 −0.1186 0.0876
Ammonia μmol/L 73.6 ± 56.4 75.0 ± 49.8  0.019 0.2995

Albumin g/L 37.3 ± 5.67 43.6 ± 10.33 0.1693 0.0247
INR 1.8 ± 0.6 1.9 ± 0.5  0.0875 0.2443

MELD 32.1 ± 4.5 28.4 ± 4.2 −0.1144 0.028