Table III.
Serum parameters in effect of MARS treatments. Albumin and INR results are also influenced by exogenous supplement. Decrease in the level of cholinesterase, and the slight increase of ammonia level shows that MARS therapy could not entirely keep up with the progression of liver failure
| Parameter | Unit | Before MARS | After MARS | Percent change | p Value |
|---|---|---|---|---|---|
| Carbamide | mmol/L | 20.5 ± 12.0 | 13.7 ± 6.7 | −0.3318 | 0.0488 |
| Creatinine | μmol/L | 213.6 ± 85.7 | 151.8 ± 51.7 | −0.2891 | 0.0155 |
| Bilirubin, total | μmol/L | 411.4 ± 250.0 | 325.6 ± 156.0 | −0.2085 | 0.0126 |
| Bilirubin, conj. | mmol/L | 318.8 ± 237.0 | 224.0 ± 147.5 | −0.2972 | 0.0077 |
| ALP | U/L | 272.7 ± 115.8 | 234.6 ± 89.5 | −0.1397 | 0.0607 |
| SGOT | U/L | 535.5 ± 746.7 | 375.9 ± 379.7 | −0.2981 | 0.0856 |
| SGPT | U/L | 420.2 ± 450.9 | 368.4 ± 353.7 | −0.1232 | 0.0152 |
| GGT | U/L | 108.9 ± 65.0 | 92.9 ± 54.5 | −0.147 | 0.0210 |
| LDH | U/L | 702.0 ± 382.3 | 462.9 ± 272.4 | −0.3406 | 0.1122 |
| Lactate | mmol/L | 7.2 ± 1.5 | 4.7 ± 1.8 | −0.3431 | N/A |
| Cholinesterase | U/L | 5897.9 ± 1514.2 | 5198.5 ± 1348.2 | −0.1186 | 0.0876 |
| Ammonia | μmol/L | 73.6 ± 56.4 | 75.0 ± 49.8 | 0.019 | 0.2995 |
| Albumin | g/L | 37.3 ± 5.67 | 43.6 ± 10.33 | 0.1693 | 0.0247 |
| INR | 1.8 ± 0.6 | 1.9 ± 0.5 | 0.0875 | 0.2443 | |
| MELD | 32.1 ± 4.5 | 28.4 ± 4.2 | −0.1144 | 0.028 | |