Figure 5.

High-frequency ultrasound imaging showing anatomical detail of xenograft growth that corresponds with ex vivo examination. HF-US images of representative xenografts at the indicated day of growth. The first column shows images from an uninfected xenograft (parental cell line). Note that by day 28 the imaging plane was changed to be able to fit the xenograft into the field of view and scan over the whole tumour to generate the 3D image. The second column shows the amplicon infected xenograft. The third column outlines the lobes visible in the amplicon xenograft. The photographs in the column are of each xenograft at day 40 showing the distinct lobes of the amplicon infected xenograft compared to the uninfected xenograft.