Table 1.
Pearson correlation coefficients of xenograft tumour volumes using different ellipsoid formulae and measured using mechanical callipers, HF-US or mass
| π/6 × L × W × H | 0.5 × L × W × H | HF-US | Mass (g) | ||
|---|---|---|---|---|---|
| 0.5 × L × W2 |
R
2
|
0.7867 |
0.7867 |
0.8576 |
0.7843 |
|
95% CI |
0.5421-0.9761 |
0.5421-0.9761 |
0.7110-0.9827 |
0.4811-0.9792 |
|
|
p |
0.0014 |
0.0014 |
0.0001 |
0.0034 |
|
| π/6 × L × W2 |
R
2
|
0.7867 |
0.7867 |
0.8576 |
0.7843 |
|
95% CI |
0.5421-0.9761 |
0.5421-0.9761 |
0.7110-0.9827 |
0.4811-0.9792 |
|
|
p |
0.0014 |
0.0014 |
0.0001 |
0.0034 |
|
| π/6 × (L × W)3/2 |
R
2
|
0.8325 |
0.8325 |
0.8636 |
0.8492 |
|
95% CI |
0.6300-0.9817 |
0.6300-0.9817 |
0.7223-0.9835 |
0.6184-0.9860 |
|
|
p |
0.0006 |
0.0006 |
0.0001 |
0.0011 |
|
| HF-US |
R
2
|
0.7993 |
0.7993 |
|
0.8470 |
|
95% CI |
0.6342-0.9724 |
0.6342-0.9724 |
|
0.6135-0.9857 |
|
|
p |
0.0002 |
0.0002 |
|
0.0012 |
|
| Mass (g) |
R
2
|
0.9254 |
0.9254 |
|
|
|
95% CI |
0.7580-0.9946 |
0.7580-0.9946 |
|
|
|
| p | 0.0005 | 0.0005 |
Three different formulae for generating in vivo tumour volumes using callipers are shown to the left and two different formulae for ex vivo tumour volumes using callipers on top. Each have been subject to pairwise comparison to determine the different correlation coefficients.