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. Author manuscript; available in PMC: 2014 Oct 15.
Published in final edited form as: Cancer Res. 2013 Oct 4;73(20):10.1158/0008-5472.CAN-13-1558-T. doi: 10.1158/0008-5472.CAN-13-1558-T

Figure 6. IL6 prevents tissue repair following Kras* inactivation.

Figure 6

(A) Experimental design, n=4~5. (B) H&E staining of iKras* and iKras*;IL6−/− mice pancreata 3 weeks post pancreatitis and 1 day, 3days and 2 weeks following Kras* inactivation. Scale bar 50μm. (C) Pathological analysis. Data represent mean ± SEM, n=3~4. The statistical difference was determined by two-sided Student’s t-test. *p<0.05, **p<0.01, #not significant. (D) Co-immunofluorescence staining for CK19 (green), amylase (red), SMA (magenta) and DAPI (blue). Scale bar 25μm. (E) Quantification of CK19 and amylase single or double positive epithelial cells in iKras* and iKras*;IL6−/− mice pancreata. Data represent mean ± SEM, n=3. The statistical difference was determined by two-sided Student’s t-test. *p<0.05, **p<0.01, ***p<0.001.