Table 4.

List of Software Available for Active Site Prediction

S.No	Software	URL	Description
1	SitesIdentify	http://www.manchester.ac.uk/bioinformatics/sitesidentify/	Sequence and geometry based
2	PAR-3D	http://sunserver.cdfd.org.in:8080/protease/PAR_3D/index.html	Structure based
3	FUZZY-OIL-DROP	http://www.bioinformatics.cm-uj.krakow.pl/activesite/	Fuzzy oil drop model
4	CASTp	http://cast.engr.uic.edu	Structure based
5	Pocket-Finder	http://www.modelling.leeds.ac.uk/pocketfinder/	Energy based
6	Q-site finder	http://www.modelling.leeds.ac.uk/qsitefinder/	Energy based
7	PASS	http://www.ccl.net/cca/software/UNIX/pass/overview.shtml	Structure based
8	SURFNET	http://www.biochem.ucl.ac.uk/~roman/surfnet/surfnet.html	Structure based
9	LIGSITECSC	http://projects.biotec.tu-dresden.de/pocket/	Based on Connolly surface
10	VOIDOO	http://xray.bmc.uu.se/usf/voidoo.html	Structure based
11	LiGandFit	http://www.phenix-online.org/documentation/ligandfit.htm	Structure based
12	Active site prediction	http://www.scfbio-iitd.res.in/dock/ActiveSite.jsp	Structure based
13	AADS	http://www.scfbio-iitd.res.in/dock/ActiveSite_new.jsp	Structure based
14	Fpocket	http://fpocket.sourceforge.net/	Based on Voronoi tessellation
15	Pocket Picker	http://gecco.org.chemie.uni-frankfurt.de/pocketpicker/index.html
16	IsoCleft	http://bcb.med.usherbrooke.ca/isocleftfinder.php	graph-matching-based method
17	metaPocket	http://sysbio.zju.edu.cn/metapocket/	Structure based
18	LIGSITEcCS	http://gopubmed2.biotec.tu-dresden.de/cgi-bin/index.php	Structure based
19	GHECOM	http://strcomp.protein.osaka-u.ac.jp/ghecom/	Structure based
20	ConCavity	http://compbio.cs.princeton.edu/concavity/	Structure based
21	POCASA	http://altair.sci.hokudai.ac.jp/g6/Research/POCASA_e.html	Structure based