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. 2013 Jun 26;1(2):e0005. doi: 10.1002/phy2.5

Table 4.

Molecules with greatest fold changes in collateral expression in WKY with comparison to SHR

WKY fold change WKY P-value SHR fold change SHR P-value Symbol Entrez gene name
3.97 0.002 1.72 0.413 ESM1 Endothelial cell-specific molecule 1
2.84 0.012 −1.00 0.989 COL12A1 Collagen, type XII, alpha 1
2.65 0.010 1.22 0.505 SLC7A1 Solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
2.48 0.019 1.41 0.422 IL1B Interleukin 1, beta
2.42 0.035 1.70 0.174 DIO3 Deiodinase, iodothyronine, type III
2.37 0.010 −0.98 0.925 ACTA1 Actin, alpha 1, skeletal muscle
2.28 0.031 −1.01 0.984 CRYAB Crystallin, alpha B
2.25 0.002 −1.05 0.899 IDI1 Isopentenyl-diphosphate delta-isomerase 1
2.25 0.007 −1.79 0.123 TGFB3 Transforming growth factor, beta 3
2.19 0.041 1.31 0.419 CYP51A1 Cytochrome P450, family 51, subfamily A, polypeptide 1
−6.45 0.039 −1.27 0.595 AGT Angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
−4.08 0.016 −2.61 0.053 SULT1A1 Sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
−3.44 0.048 −1.32 0.243 TNXA Tenascin XA
−2.93 0.049 −2.08 0.679 JUN Jun proto-oncogene
−2.86 0.000 −1.97 0.128 GSTT2 Glutathione S-transferase theta 2
−2.84 0.010 −2.21 0.034 ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
−2.74 0.044 −1.65 0.113 EPHX1 Epoxide hydrolase 1, microsomal (xenobiotic)
−2.68 0.001 −2.32 0.623 FMOD Fibromodulin
−2.49 0.029 −1.86 0.182 EEF2K Eukaryotic elongation factor-2 kinase
−2.48 0.025 −0.68 0.831 CX3CL1 Chemokine (C-X3-C motif) ligand 1

IPA, Ingenuity® pathway analysis; WKY, Wistar Kyoto; SHR, spontaneously hypertensive rat.