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. 2013 Jul 21;1(2):e00035. doi: 10.1002/phy2.35

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© 2013 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society

Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.

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Long-term plasticity. (A) High-frequency stimulation (HFS)-induced long-term potentiation (LTP) is present in CA1 (black circle) and subiculum (SUB; open circles) under control conditions (n = 5). (B) Exposure to acute stress (n = 6) reduces the magnitude of HFS-induced LTP in CA1 (black circles) and SUB (open circles). (C) Summary of control and acute stress treatment on HFS-induced LTP in CA1 and SUB. (D) Low-frequency stimulation (LFS)-induced late-developing potentiation is present in SUB (open circles) but not CA1 (black circles) in control rats (n = 6). (E) Exposure to acute stress (n = 6) disrupts LFS-induced late-developing potentiation in SUB (open circles) but has no effect on CA1 (black circles) plasticity. (F) Summary of control and acute stress treatment following LFS in CA1 and SUB. *Significantly greater potentiation in the control than acutely stressed rats.