Table 1.

Gene sets related to aversive memory (testing sample)

Pathway	Pathway URL	Gene set P (nominal)	Gene set P (FDR)	Significant gene set genes (N)	Mapped gene set genes (N)	All gene set genes (N)
VEGF pathway	biocarta.com/pathfiles/ h_VEGFPATHWAY.asp	<0.001	0.011	10	21	28
IL1R pathway	biocarta.com/pathfiles/ h_IL1RPATHWAY.asp	<0.001	0.013	13	24	33
HSA04730 LONG-TERM DEPRESSION	genome.jp/dbget-bin/www_bget? pathway+hsa04730	<0.001	0.019	33	67	76
HSA04080 NEUROACTIVE LIGAND RECEPTOR INTERACTION	genome.jp/dbget-bin/www_bget? pathway+hsa04080	<0.001	0.036	69	175	254

All gene set genes, all genes of a given gene set, i.e., mapped and unmapped genes; mapped gene set genes, gene set genes containing at least one intragenic SNP and therefore included in the i-GSEA analysis; significant gene set genes, genes mapped with at least one of the top 5% of all nominally significant SNPs (Materials and Methods).