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Reduced Na+/H+ exchange prevents neuronal superoxide production after ischemia–reperfusion. (A and B) Eth fluorescence (red) and 4HNE (green) in representative hippocampal sections harvested 30 min after ischemia–reperfusion show reduced superoxide formation in NHE1+/− mice. (Scale bar: 60 µm in A, 15 µm in B.) (C and D) show quantified data; n = 4, *P < 0.05 vs. all other groups.
