Table 1.

dNTP pools in nrdA mutator mutants

nrdA allele	RNR site	dATP	dTTP	dGTP	dCTP	n
Wild type	None	11.9 ± 3.8	5.8 ± 2.0	3.1 ± 1.2	2.4 ± 2.4	11
G295S	Specificity	7.5 ± 1.4	10.3 ± 1.6	5.3 ± 2.0	3.7 ± 1.9	12
A301T	Specificity	6.9 ± 0.9	8.8 ± 1.1	2.3 ± 1.4	8.0 ± 2.7	5
A301V	Specificity	6.9 ± 2.2	9.9 ± 3.4	6.0 ± 2.6	8.4 ± 4.7	13
S37L	Activity	34	13	4.7	36	2
H46Y	Activity	58	15	6.9	74	2

n, the number of independent measurements. All dNTP levels are relative to ATP, as described (14).