Figure 4.

K–L Divergences between monomeric and dimeric CXCR4:SDF-1 complexes show minimal divergence for the monomeric complex. Divergence is shown between the unsulfated (2k04) and sulfated (2k05) conformers for simulation of the dimeric complex (left, half of the dimer is shown), and between the unsulfated (2k04) and sulfated (2k05) conformers for simulation of the monomeric complex (right). Y7, Y12, and Y21 are shown as purple sticks. [Color figure can be viewed in the online issue, which is available at http://wileyonlinelibrary.com.]