Figure 2.
Telodendrimer addition to nanoparticle formation changed aggregation levels and size tenability. Dynamic light scattering (DLS) was used to assess several biophysical properties of the TD-NLP particles. (A) The size distribution of TD-NLPs measured by dynamic light scattering. TD-NLPs demonstrated an improved homogeneity compared to normal DMPC-NLP. (B) Total aggregations of various TD-NLPs are significantly less as compared to normal DMPC-NLP (p < 0.01). (C) PEG tail length and size of the TD-NLPs are significantly correlated (PEG2K vs. PEG5K, p < 0.01). [Color figure can be viewed in the online issue, which is available at http://wileyonlinelibrary.com.]