Table 3.
Odds ratio (OR) with 95% confidence interval (CI) of prostate cancer according to categories of coffee consumption, King County, Washington, 2002-2005
| Categories of coffee consumption (cups/unit of time) |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ≤1/week | 2-6/week | 1/day | 2-3/day | ≥4/day | P trend | Cup/week increment | ||||||
|
|
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| OR | OR | (95% CI) | OR | (95% CI) | OR | (95% CI) | OR | (95% CI) | OR | (95% CI | ||
|
|
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| Controls, No. | 257 | 100 | 146 | 253 | 104 | |||||||
| All prostate cancers, No. | 246 | 113 | 154 | 273 | 108 | |||||||
| Age-adjusted OR (95% CI) | 1.00 | 1.18 | (0.86, 1.63) | 1.10 | (0.82, 1.46) | 1.12 | (0.88, 1.43) | 1.08 | (0.79, 1.49) | 0.50 | 1.00 | (0.99, 1.01) |
| Multivariable-adjusted OR (95% CI)* | 1.00 | 1.22 | (0.88, 1.69) | 1.13 | (0.84, 1.51) | 1.16 | (0.90, 1.50) | 1.16 | (0.82, 1.63) | 0.32 | 1.00 | (0.99, 1.01) |
| Gleason 2-7(3+4) cancers, No. | 207 | 87 | 124 | 222 | 91 | |||||||
| Age-adjusted OR (95% CI) | 1.00 | 1.08 | (0.77, 1.52) | 1.06 | (0.78, 1.43) | 1.10 | (0.85, 1.42) | 1.09 | (0.78, 1.52) | 0.51 | 1.00 | (0.99, 1.01) |
| Multivariable-adjusted OR (95% CI)* | 1.00 | 1.13 | (0.80, 1.59) | 1.09 | (0.80, 1.49) | 1.15 | (0.88, 1.51) | 1.19 | (0.83, 1.71) | 0.27 | 1.00 | (0.99, 1.01) |
| Gleason 7(4+3)-10 cancers, No. | 39 | 28 | 30 | 51 | 18 | |||||||
| Age-adjusted OR (95% CI) | 1.00 | 1.79 | (1.04, 3.08) | 1.28 | (0.76, 2.15) | 1.26 | (0.80, 1.98) | 1.11 | (0.61, 2.04) | 0.75 | 1.00 | (0.98, 1.01) |
| Multivariable-adjusted OR (95% CI)* | 1.00 | 1.72 | (1.00, 2.97) | 1.30 | (0.77, 2.19) | 1.25 | (0.78, 1.99) | 1.04 | (0.55, 1.96) | 0.81 | 1.00 | (0.98, 1.01) |
| Local stage cancers, No. | 200 | 95 | 123 | 222 | 85 | |||||||
| Age-adjusted OR (95% CI) | 1.00 | 1.22 | (0.87, 1.71) | 1.07 | (0.79, 1.45) | 1.11 | (0.85, 1.43) | 1.05 | (0.74, 1.47) | 0.70 | 1.00 | (0.99, 1.01) |
| Multivariable-adjusted OR (95% CI)* | 1.00 | 1.25 | (0.89, 1.76) | 1.07 | (0.79, 1.47) | 1.13 | (0.86, 1.49) | 1.12 | (0.78, 1.61) | 0.50 | 1.00 | (0.99, 1.01) |
| Regional/distant stage cancers, No. | 46 | 18 | 31 | 51 | 23 | |||||||
| Age-adjusted OR (95% CI) | 1.00 | 1.02 | (0.56, 1.85) | 1.24 | (0.75, 2.06) | 1.20 | (0.77, 1.86) | 1.30 | (0.75, 2.26) | 0.27 | 1.01 | (0.99, 1.02) |
| Multivariable-adjusted OR (95% CI)* | 1.00 | 1.01 | (0.55, 1.83) | 1.27 | (0.77, 2.11) | 1.23 | (0.78, 1.93) | 1.33 | (0.74, 2.38) | 0.24 | 1.01 | (0.99, 1.02) |
*
Multivariable models were adjusted for age, race, first-degree family history of prostate cancer, smoking status, and history of prostate cancer screening.