Table 4.
Rest | 1st Air | Heliox | 2nd Air | |
---|---|---|---|---|
(mmHg) | 10 ± 1 | 28 ± 2§ | 28 ± 2§ | 29 ± 2§ |
pH | 7.32 ± 0.01 | 7.34 ± 0.01§ | 7.34 ± 0.01§ | 7.32 ± 0.02 |
Toes (°C) | 37.3 ± 0.1 | 37.6 ± 0.1§* | 38.1 ± 0.1§ | 38.3 ± 0.1§* |
K+ (mmol l−1) | 3.6 ± 0.1 | 5.4 ± 0.1§ | 5.3 ± 0.1§ | 5.3 ± 0.1§ |
HCO3− (mmol l−1) | 17 ± 1 | 19 ± 0.4§ | 18 ± 1§ | 19 ± 1§ |
Hb (g dl−1) | 12.5 ± 0.2 | 13.1 ± 0.2§ | 13.2 ± 0.2§ | 13.3 ± 0.2§ |
VT (l) | 0.7 ± 0.03 | 1.8 ± 0.1§ | 1.9 ± 0.1§ | 1.9 ± 0.1§ |
f (beats min-1) | 17 ± 1 | 40 ± 2§* | 48 ± 3§ | 47 ± 3§ |
(l min−1) | 0.32 ± 0.01 | 2.6 ± 0.1§* | 2.9 ± 0.1§ | 2.9 ± 0.1§ |
(l min−1) | 0.26 ± 0.01 | 2.3 ± 0.1§* | 2.7 ± 0.1§ | 2.8 ± 0.1§ |
RER | 0.81 ± 0.02 | 0.87 ± 0.01§* | 0.94 ± 0.01§ | 0.97 ± 0.02§ |
VD/VT | 0.2 ± 0.01 | 0.14 ± 0.01§ | 0.16 ± 0.01§ | 0.17 ± 0.01 |
Ti (%) | 33 ± 1 | 48 ± 1§ | 48 ± 1§ | 47 ± 1§ |
WOBel (%total) | 69 ± 2 | 55 ± 2§* | 60 ± 2§ | 51 ± 2§* |
WOBres (%total) | 31 ± 2 | 45 ± 2§* | 40 ± 2§ | 49 ± 2§* |
Values are mean ± SEM. , alveolar oxygen tension; , alveolar-to-arterial oxygen difference; Toes, oesophageal temperature; Hb, haemoglobin; VT, tidal volume; f, breathing frequency; , oxygen consumption; , carbon dioxide production; RER, respiratory exchange ratio; VD, physiological deadspace; Ti, inspiratory time; VT, tidal volume; WOBel, elastic work of breathing; WOBRes, resistive work of breathing. §Different from rest; *different from heliox, P < 0.05.