Table 2.
IC50 values of Compound IVa-e , Va-h and Tamoxifen on MCF7 and HT29 cell lines by MTT assay
| Comp. ID. |
MCF-7
a
|
HT29
b
|
||
|---|---|---|---|---|
| IC 50 (µM) | RSD% | IC 50 (µM) | RSD% | |
| IV a | 6 | 7.9 | 13.13 | 4.3 |
| IV b | 9.3 | 5.0 | 10.75 | 6.8 |
| IV c | >100 | - | 38.27 | 4.3 |
| IV d | 42.07 | 3.8 | 7.51 | 6.9 |
| IV e | 8.54 | 6.7 | >100 | - |
| V a | >100 | - | >100 | - |
| V b | >100 | - | >100 | - |
| V c | >100 | - | >100 | - |
| V d | >100 | - | 90.31 | 2.1 |
| V e | >100 | - | >100 | - |
| V f | >100 | - | >100 | - |
| V g | 27.2 | 7.1 | 61.9 | 3.4 |
| V h | 65.86 | 8.1 | >100 | - |
| TAMOXIFEN | 6.05 | 4.9 | 10.36 | 3.7 |
a human breast adenocarcinoma cell line. b human colon adenocarcinoma cell line