Table 4.
Variant | Allele frequency (A) |
Absolute difference in allele frequency |
P | Experiment- wise P |
Rank of P |
Distance to next variant (nucleotides) |
Location | |
---|---|---|---|---|---|---|---|---|
Control | Case | |||||||
A. Caucasian | ||||||||
RIMS2: Regulating synaptic membrane exocytosis protein 2 (chromosome 8q22.3) | ||||||||
rs2511571 | 0.59 | 0.66 | 0.07 | 0.0007 | 1 | 146 | 2,031 | intron |
rs2511576 | 0.63 | 0.71 | 0.08 | 0.0007 | 1 | 178 | 12,304 | intron |
rs1156813 | 0.33 | 0.26 | 0.07 | 0.0003 | 0.98 | 34 | intron | |
B. African American i. | ||||||||
i. CMYA3: cardiomyopathy associated 3 (chromosome 2q24.3) | ||||||||
rs1429931 | 0.73 | 0.79 | 0.07 | 0.0238 | 1 | 364 | 428 | intron |
rs6706115 | 0.67 | 0.74 | 0.08 | 0.0079 | 1 | 136 | 2,913 | intron |
rs10497320 | 0.20 | 0.17 | 0.03 | 0.0079 | 1 | intron | ||
ii. No gene within 100,000 nucleotides (chromosome 13q13.1) | ||||||||
rs1937387 | 0.63 | 0.54 | 0.09 | 0.0079 | 1 | 157 | 3,132 | |
rs2876780 | 0.77 | 0.66 | 0.11 | 0.0079 | 1 | 155 | 5,877 | |
rs9318868 | 0.73 | 0.63 | 0.10 | 0.0079 | 1 |