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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: FEBS J. 2013 Sep 23;280(22):10.1111/febs.12499. doi: 10.1111/febs.12499

Figure 2. Average hydropathy, amphipathicity and similarity (AveHAS) plots based on a ClustalX multiple alignment.

Figure 2

All members of all TOG Superfamily families from TCDB were included except for the GPCR (see Fig. S10) family. The plot reveals 8 well conserved average TMSs. However, as many as 6 poorly conserved peaks of hydrophobicity can be seen representing additional potential TMSs in the non-homologous regions of some proteins.