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. Author manuscript; available in PMC: 2013 Nov 18.
Published in final edited form as: Nat Biotechnol. 2009 Nov 1;27(11):10.1038/nbt.1582. doi: 10.1038/nbt.1582

Figure 1. Flowchart of the systematic iterative integration process.

Figure 1

Genome-wide data generated by multiple HT platforms, including RNAP binding regions, transcripts, transcription start sites (TSS) and peptides, were integrated based on the work flow depicted. An iterative process using HT data generated from cells grown under different conditions formed the basis for elucidation of the TU architecture. (RBR) RNA polymerase binding region (S, static map; D, dynamic map), (RTS) RNAP-guided transcript segment (RTS), (pORF) potential ORF.