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. Author manuscript; available in PMC: 2014 Aug 5.
Published in final edited form as: J Mol Microbiol Biotechnol. 2013 Aug 5;23(0):10.1159/000351625. doi: 10.1159/000351625

Figure 8.

Figure 8

Both the MCP conformation and the relative activities of CheR and CheB determine the MCP methylation state. Conversion of the methylatable glutamates in an MCP to alanines by site specific mutagenesis blocks adaptation, but some adaptation still occurs due to cooperativity within the MCP lattice that results from methylation changes in other MCPs. SAM, S-adenosylmethionine; MeOH, methanol.