Figure 9.

¹²⁵I-α-NDP-MSH radioligand saturation binding to different platyfish Mc4 receptor constructs expressed in HEK-293 cells. The results of representative saturation binding experiments with the radioligand ¹²⁵I-α-NDP-MSH are shown as specific (square) and nonspecific binding (circle). (Top) Saturation binding at the platyfish Mc4r-S. (Middle) Saturation binding at platyfish Mc4r-L. (Bottom) Saturation binding at platyfish Mc4r-O. The results of the saturation binding experiments are summarized in Table 1.