Figure 4. Mediation of the ulnar nerve in the inhibitory effects of HT7 stimulation on cocaine-induced locomotion.
A: The inhibitory effects of HT7 on cocaine locomotion are completely blocked by severing the ulnar nerve (Ulnar+HT7), but not by radial and median nerves (Rad/Med+HT7) (Con, n=12; HT7, n=12; Ulnar+HT7, n=11; Rad/Med+HT7, n=9). Data are analyzed by one way ANOVA with Holm-Sidak post hoc comparison. B: Mechanical stimulation of needle inserted into the tip of the 5th digit produced a similar effect). Data are presented as mean ± SEM and analyzed by two-way repeated ANOVA with Holm-Sidak post hoc comparison. * indicates significance at p≤ 0.05.