Table 3. Statistical analysis of C20orf54 expression and clinicopathologic factors in CIN and cervical cancer.
| Characteristics | N | C20orf54 expression | Z | P | |||
| − | + | ++ | +++ | ||||
| Normal mucousepithelia | 50 | 18 | 25 | 7 | 0 | 42.485 | <0.001* |
| CIN II–III | 46 | 14 | 15 | 12 | 5 | ||
| CSCC | 50 | 4 | 8 | 14 | 24 | ||
| Differentiation | |||||||
| Moderate/well | 22 | 2 | 3 | 7 | 10 | −1.238 | 0.216 |
| Poor | 28 | 2 | 5 | 7 | 14 | ||
| L/N metastasis | |||||||
| Negative | 24 | 1 | 6 | 3 | 14 | −0.164 | 0.87 |
| Positive | 26 | 3 | 2 | 11 | 10 | ||
| Stage | |||||||
| II and IIIa | 21 | 3 | 6 | 8 | 4 | −2.625 | 0.009 |
| IIIb and IV | 29 | 1 | 2 | 6 | 20 | ||
L/N metastasis: Lymph node metastasis. −: Negative;+: Weak positive;++: Medium positive;+++: Strong positive. Mann-Whitney test were used to test continuous variables for differences in IHC staining scores between tumor and normal tissues for the C20orf54. * was shown for comparison with CIN, CSCC and normal control groups.