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a) Mean values of all animals in a group were calculated. Temporal changes are shown as continuous bar graphs (mean ± SD). b) Time-flow curves of all mice in each group. As the dose of saxatilin or rt-PA increases, the time to recanalization and the frequency of reocclusion decreases. Saxatilin showed relatively short time to recanalization and low frequency of reocclusion compared with rt-PA.
