Table 2. Statistics of two-group Region of Interest analysis: HV vs All_ALC.
| Region of Interest | Whole Model a F ratio, Prob > F |
Student’s t
|
% Difference in FA | ||
|---|---|---|---|---|---|
| Group | Level b | Least Square Mean (SE c) of FA | HV > All_ALC | ||
| Anterior Commissure | 4.21, 0.0053 | HV | A | 0.39 (0.020) | 20.5 |
| All_ALC | B | 0.31 (0.014) | |||
| Fornix | 6.33, 0.0004 | HV | A | 0.74 (0.019) | 14.9 |
| All_ALC | B | 0.63 (0.013) | |||
| Genu | 4.02, 0.0070 | HV | A | 0.84 (0.012) | 3.6 |
| All_ALC | A | 0.81 (0.008) | |||
| Splenium+ | 5.57, 0.0009 | HV | A | 0.86 (0.013) | 1.2 |
| All_ALC | A | 0.85 (0.010) | |||
| Right IFO | 12.49, <0.0001 | HV | A | 0.62 (0.011) | 9.7 |
| All_ALC | B | 0.56 (0.008) | |||
| Right dorsal cingulum bundle | 0.39, 0.82 | HV | A | 0.53 (0.019) | 3.8 |
| All_ALC | A | 0.51 (0.013) | |||
| Left dorsal cingulum bundle | 2.06, 0.10 | HV | A | 0.61 (0.017) | 4.9 |
| All_ALC | A | 0.58 (0.012) | |||
a The whole model is corrected for group, sex, age, and group by sex. b Groups not sharing the same letter are significantly different. c Standard error. + The observed significance of the whole model GLM in the splenium was the result of an effect of age, not group, on FA.